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Research Article

Aptamer Based, Non-PCR, Non-Serological Detection of Chagas Disease Biomarkers in Trypanosoma cruzi Infected Mice

  • Rana Nagarkatti,

    Affiliation: Laboratory of Emerging Pathogens, Division of Emerging and Transfusion Transmitted Diseases, Center for Biologics Evaluation and Research, U. S. Food and Drug Administration, Bethesda, Maryland, United States of America

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  • Fernanda Fortes de Araujo,

    Affiliation: Laboratory of Emerging Pathogens, Division of Emerging and Transfusion Transmitted Diseases, Center for Biologics Evaluation and Research, U. S. Food and Drug Administration, Bethesda, Maryland, United States of America

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  • Charu Gupta,

    Affiliation: Laboratory of Emerging Pathogens, Division of Emerging and Transfusion Transmitted Diseases, Center for Biologics Evaluation and Research, U. S. Food and Drug Administration, Bethesda, Maryland, United States of America

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  • Alain Debrabant mail

    alain.debrabant@fda.hhs.gov

    Affiliation: Laboratory of Emerging Pathogens, Division of Emerging and Transfusion Transmitted Diseases, Center for Biologics Evaluation and Research, U. S. Food and Drug Administration, Bethesda, Maryland, United States of America

    X
  • Published: January 16, 2014
  • DOI: 10.1371/journal.pntd.0002650

About the Authors

Rana Nagarkatti, Fernanda Fortes de Araujo, Charu Gupta, Alain Debrabant
Laboratory of Emerging Pathogens, Division of Emerging and Transfusion Transmitted Diseases, Center for Biologics Evaluation and Research, U. S. Food and Drug Administration, Bethesda, Maryland, United States of America

Corresponding Author

Email: alain.debrabant@fda.hhs.gov

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: RN AD. Performed the experiments: RN FFA CG. Analyzed the data: RN FFA AD. Contributed reagents/materials/analysis tools: RN FFA AD. Wrote the paper: RN FFA AD.