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Research Article

Targeting Echinococcus multilocularis Stem Cells by Inhibition of the Polo-Like Kinase EmPlk1

  • Andreas Schubert,

    Affiliation: University of Würzburg, Institute of Hygiene and Microbiology, Würzburg, Germany

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  • Uriel Koziol,

    Affiliations: University of Würzburg, Institute of Hygiene and Microbiology, Würzburg, Germany, Universidad de la República, Facultad de Ciencias, Sección Bioquímica y Biología Molecular, Montevideo, Uruguay

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  • Katia Cailliau,

    Affiliation: EA4479, IFR147, Laboratoire de Régulation des Signaux de Division, SN3, University Lille 1, Villeneuve d'Ascq, France

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  • Mathieu Vanderstraete,

    Affiliation: Center for Infection and Immunology of Lille, Inserm U1019, CNRS-UMR 8204, University Lille 2, Institut Pasteur de Lille, Lille, France

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  • Colette Dissous,

    Affiliation: Center for Infection and Immunology of Lille, Inserm U1019, CNRS-UMR 8204, University Lille 2, Institut Pasteur de Lille, Lille, France

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  • Klaus Brehm mail

    kbrehm@hygiene.uni-wuerzburg.de

    Affiliation: University of Würzburg, Institute of Hygiene and Microbiology, Würzburg, Germany

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  • Published: June 05, 2014
  • DOI: 10.1371/journal.pntd.0002870

About the Authors

Andreas Schubert, Uriel Koziol, Klaus Brehm
University of Würzburg, Institute of Hygiene and Microbiology, Würzburg, Germany
Uriel Koziol
Universidad de la República, Facultad de Ciencias, Sección Bioquímica y Biología Molecular, Montevideo, Uruguay
Katia Cailliau
EA4479, IFR147, Laboratoire de Régulation des Signaux de Division, SN3, University Lille 1, Villeneuve d'Ascq, France
Mathieu Vanderstraete, Colette Dissous
Center for Infection and Immunology of Lille, Inserm U1019, CNRS-UMR 8204, University Lille 2, Institut Pasteur de Lille, Lille, France

Corresponding Author

Email: kbrehm@hygiene.uni-wuerzburg.de

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: KB CD. Performed the experiments: AS UK KC MV. Analyzed the data: AS UK KC MV CD KB. Contributed reagents/materials/analysis tools: AS UK MV. Wrote the paper: KB CD.