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Considerations in the Design of Clinical Trials to Test Novel Entomological Approaches to Dengue Control

  • Marcel Wolbers,

    Affiliations: Oxford University Clinical Research Unit, Hospital for Tropical Diseases, Ho Chi Minh City, Viet Nam, Centre for Tropical Medicine, Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom

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  • Immo Kleinschmidt,

    Affiliation: MRC Tropical Epidemiology Group, Department of Infectious Disease Epidemiology, London School of Hygiene and Tropical Medicine, London, United Kingdom

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  • Cameron P. Simmons mail,

    csimmons@oucru.org

    Affiliations: Oxford University Clinical Research Unit, Hospital for Tropical Diseases, Ho Chi Minh City, Viet Nam, Centre for Tropical Medicine, Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom

    X
  • Christl A. Donnelly

    Affiliation: Medical Research Council Centre for Outbreak Analysis and Modelling, Department of Infectious Disease Epidemiology, School of Public Health, Imperial College London, London, United Kingdom

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  • Published: November 29, 2012
  • DOI: 10.1371/journal.pntd.0001937
  • Featured in PLOS Collections

About the Authors

Marcel Wolbers, Cameron P. Simmons
Oxford University Clinical Research Unit, Hospital for Tropical Diseases, Ho Chi Minh City, Viet Nam
Marcel Wolbers, Cameron P. Simmons
Centre for Tropical Medicine, Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom
Immo Kleinschmidt
MRC Tropical Epidemiology Group, Department of Infectious Disease Epidemiology, London School of Hygiene and Tropical Medicine, London, United Kingdom
Christl A. Donnelly
Medical Research Council Centre for Outbreak Analysis and Modelling, Department of Infectious Disease Epidemiology, School of Public Health, Imperial College London, London, United Kingdom

Corresponding Author

Email: csimmons@oucru.org

Competing Interests

Cameron Simmons is an investigator in the Eliminate Dengue Project, which aims to use Wolbachia-infected Aedes aegypti mosquitoes to reduce dengue transmission.