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Research Article

A Global Comparison of the Human and T. brucei Degradomes Gives Insights about Possible Parasite Drug Targets

  • Susan T. Mashiyama,

    Affiliations: Department of Bioengineering and Therapeutic Sciences, California Institute for Quantitative Biomedical Research (QB3), University of California San Francisco, San Francisco, California, United States of America, Center for Discovery and Innovation in Parasitic Diseases, and Department of Pathology, QB3, University of California San Francisco, San Francisco, California, United States of America

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  • Kyriacos Koupparis,

    Affiliation: Center for Discovery and Innovation in Parasitic Diseases, and Department of Pathology, QB3, University of California San Francisco, San Francisco, California, United States of America

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  • Conor R. Caffrey,

    Affiliation: Center for Discovery and Innovation in Parasitic Diseases, and Department of Pathology, QB3, University of California San Francisco, San Francisco, California, United States of America

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  • James H. McKerrow mail,

    jmck@cgl.ucsf.edu (JHM); babbitt@cgl.ucsf.edu (PCB)

    Affiliation: Center for Discovery and Innovation in Parasitic Diseases, and Department of Pathology, QB3, University of California San Francisco, San Francisco, California, United States of America

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  • Patricia C. Babbitt mail

    jmck@cgl.ucsf.edu (JHM); babbitt@cgl.ucsf.edu (PCB)

    Affiliation: Department of Bioengineering and Therapeutic Sciences, California Institute for Quantitative Biomedical Research (QB3), University of California San Francisco, San Francisco, California, United States of America

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  • Published: December 06, 2012
  • DOI: 10.1371/journal.pntd.0001942

About the Authors

Susan T. Mashiyama, Patricia C. Babbitt
Department of Bioengineering and Therapeutic Sciences, California Institute for Quantitative Biomedical Research (QB3), University of California San Francisco, San Francisco, California, United States of America
Susan T. Mashiyama, Kyriacos Koupparis, Conor R. Caffrey, James H. McKerrow
Center for Discovery and Innovation in Parasitic Diseases, and Department of Pathology, QB3, University of California San Francisco, San Francisco, California, United States of America

Corresponding Authors

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: STM PCB KK. Performed the experiments: STM KK CRC. Analyzed the data: STM KK CRC. Contributed reagents/materials/analysis tools: JHM PCB. Wrote the paper: STM PCB KK CRC JHM.