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Research Article

IFN-γ Production to Leishmania Antigen Supplements the Leishmania Skin Test in Identifying Exposure to L. braziliensis Infection

  • Daniel Schnorr equal contributor,

    equal contributor Contributed equally to this work with: Daniel Schnorr, Aline C. Muniz

    Affiliations: Serviço de Imunologia, Complexo Hospitalar Universitário Prof. Edgard Santos, Universidade Federal da Bahia, Salvador, Brazil, Columbia University College of Physicians and Surgeons, New York, New York, United States of America

    Current address: Department of Emergency Medicine, Highland General Hospital, Oakland, California, United States of America

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  • Aline C. Muniz equal contributor,

    equal contributor Contributed equally to this work with: Daniel Schnorr, Aline C. Muniz

    Affiliation: Serviço de Imunologia, Complexo Hospitalar Universitário Prof. Edgard Santos, Universidade Federal da Bahia, Salvador, Brazil

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  • Sara Passos,

    Affiliations: Serviço de Imunologia, Complexo Hospitalar Universitário Prof. Edgard Santos, Universidade Federal da Bahia, Salvador, Brazil, Instituto Nacional de Ciência e Tecnologia de Doenças Tropicais (CNPq/MCT), Salvador, Brazil

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  • Luiz H. Guimaraes,

    Affiliations: Serviço de Imunologia, Complexo Hospitalar Universitário Prof. Edgard Santos, Universidade Federal da Bahia, Salvador, Brazil, Instituto Nacional de Ciência e Tecnologia de Doenças Tropicais (CNPq/MCT), Salvador, Brazil

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  • Ednaldo L. Lago,

    Affiliation: Serviço de Imunologia, Complexo Hospitalar Universitário Prof. Edgard Santos, Universidade Federal da Bahia, Salvador, Brazil

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  • Olívia Bacellar,

    Affiliations: Serviço de Imunologia, Complexo Hospitalar Universitário Prof. Edgard Santos, Universidade Federal da Bahia, Salvador, Brazil, Instituto Nacional de Ciência e Tecnologia de Doenças Tropicais (CNPq/MCT), Salvador, Brazil

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  • Marshall J. Glesby,

    Affiliation: Division of Infectious Diseases, Department of Medicine, Weill Cornell Medical College, New York, New York, United States of America

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  • Edgar M. Carvalho mail

    imuno@ufba.br

    Affiliations: Serviço de Imunologia, Complexo Hospitalar Universitário Prof. Edgard Santos, Universidade Federal da Bahia, Salvador, Brazil, Instituto Nacional de Ciência e Tecnologia de Doenças Tropicais (CNPq/MCT), Salvador, Brazil

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  • Published: December 20, 2012
  • DOI: 10.1371/journal.pntd.0001947

About the Authors

Daniel Schnorr, Aline C. Muniz, Sara Passos, Luiz H. Guimaraes, Ednaldo L. Lago, Olívia Bacellar, Edgar M. Carvalho
Serviço de Imunologia, Complexo Hospitalar Universitário Prof. Edgard Santos, Universidade Federal da Bahia, Salvador, Brazil
Daniel Schnorr
Columbia University College of Physicians and Surgeons, New York, New York, United States of America
Sara Passos, Luiz H. Guimaraes, Olívia Bacellar, Edgar M. Carvalho
Instituto Nacional de Ciência e Tecnologia de Doenças Tropicais (CNPq/MCT), Salvador, Brazil
Marshall J. Glesby
Division of Infectious Diseases, Department of Medicine, Weill Cornell Medical College, New York, New York, United States of America

Corresponding Author

Email: imuno@ufba.br

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: DS MJG EMC. Performed the experiments: ACM SP ELL. Analyzed the data: DS LHG OB MJG EMC. Contributed reagents/materials/analysis tools: ACM SP OB. Wrote the paper: DS ACM OB MJG EMC. Medical doctor and researcher of the endemic area, responsible for patients' diagnoses and treatment: LHG. Field assistance: ELL.