Advertisement
Research Article

Arginase Activity in the Blood of Patients with Visceral Leishmaniasis and HIV Infection

  • Yegnasew Takele equal contributor,

    equal contributor Contributed equally to this work with: Yegnasew Takele, Tamrat Abebe

    Affiliation: Gondar University Leishmaniasis Research and Treatment Centre, University of Gondar, Gondar, Ethiopia

    X
  • Tamrat Abebe equal contributor,

    equal contributor Contributed equally to this work with: Yegnasew Takele, Tamrat Abebe

    Affiliation: Department of Microbiology, Immunology, Parasitology and Pathology, Addis Ababa University, Addis Ababa, Ethiopia

    X
  • Teklu Weldegebreal,

    Affiliation: Gondar University Leishmaniasis Research and Treatment Centre, University of Gondar, Gondar, Ethiopia

    X
  • Asrat Hailu,

    Affiliation: Department of Microbiology, Immunology, Parasitology and Pathology, Addis Ababa University, Addis Ababa, Ethiopia

    X
  • Workagegnehu Hailu,

    Affiliation: College of Medicine and Health Sciences, University of Gondar, Gondar, Ethiopia

    X
  • Zewdu Hurissa,

    Affiliation: Gondar University Leishmaniasis Research and Treatment Centre, University of Gondar, Gondar, Ethiopia

    X
  • Jemal Ali,

    Affiliation: Department of Microbiology, Immunology and Parasitology, School of Biomedical and Laboratory Sciences, University of Gondar, Gondar, Ethiopia

    X
  • Ermiyas Diro,

    Affiliation: Gondar University Leishmaniasis Research and Treatment Centre, University of Gondar, Gondar, Ethiopia

    X
  • Yifru Sisay,

    Affiliation: College of Medicine and Health Sciences, University of Gondar, Gondar, Ethiopia

    X
  • Tom Cloke,

    Affiliation: Department of Medicine, Section of Immunology, Imperial College London, London, United Kingdom

    X
  • Manuel Modolell,

    Affiliation: Department of Cellular Immunology, Max-Planck-Institute for Immunobiology and Epigenetics, Freiburg, Germany

    X
  • Markus Munder,

    Affiliation: Third Department of Medicine (Hematology, Oncology, and Pneumology), University Medical Center Mainz, Mainz, Germany

    X
  • Fabienne Tacchini-Cottier,

    Affiliation: Department of Biochemistry, WHO Immunology Research and Training Center, University of Lausanne, Lausanne, Switzerland

    X
  • Ingrid Müller,

    Affiliation: Department of Medicine, Section of Immunology, Imperial College London, London, United Kingdom

    X
  • Pascale Kropf mail

    Pascale.Kropf@lshtm.ac.uk

    Affiliation: Department of Immunology and Infection, London School of Hygiene and Tropical Medicine, London, United Kingdom

    X
  • Published: January 17, 2013
  • DOI: 10.1371/journal.pntd.0001977

About the Authors

Yegnasew Takele, Teklu Weldegebreal, Zewdu Hurissa, Ermiyas Diro
Gondar University Leishmaniasis Research and Treatment Centre, University of Gondar, Gondar, Ethiopia
Tamrat Abebe, Asrat Hailu
Department of Microbiology, Immunology, Parasitology and Pathology, Addis Ababa University, Addis Ababa, Ethiopia
Workagegnehu Hailu, Yifru Sisay
College of Medicine and Health Sciences, University of Gondar, Gondar, Ethiopia
Jemal Ali
Department of Microbiology, Immunology and Parasitology, School of Biomedical and Laboratory Sciences, University of Gondar, Gondar, Ethiopia
Tom Cloke, Ingrid Müller
Department of Medicine, Section of Immunology, Imperial College London, London, United Kingdom
Manuel Modolell
Department of Cellular Immunology, Max-Planck-Institute for Immunobiology and Epigenetics, Freiburg, Germany
Markus Munder
Third Department of Medicine (Hematology, Oncology, and Pneumology), University Medical Center Mainz, Mainz, Germany
Fabienne Tacchini-Cottier
Department of Biochemistry, WHO Immunology Research and Training Center, University of Lausanne, Lausanne, Switzerland
Pascale Kropf
Department of Immunology and Infection, London School of Hygiene and Tropical Medicine, London, United Kingdom

Corresponding Author

Email: Pascale.Kropf@lshtm.ac.uk

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: T. Abebe T. Cloke I. Müller P. Kropf. Performed the experiments: Y. Takele T. Abebe T. Weldegebreal P. Kropf. Analyzed the data: Y. Takele T. Abebe T. Weldegebreal A. Hailu W. Hailu Z. Hurissa J. Ali E. Diro Y. Sisay T. Cloke M. Modolell M. Munder F. Tacchini-Cottier I. Müller P. Kropf. Wrote the paper: Y. Takele T. Abebe T. Weldegebreal F. Tacchini-Cottier I. Müller P. Kropf.