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Research Article

Cross-reactive Neutralizing Antibody Responses to Enterovirus 71 Infections in Young Children: Implications for Vaccine Development

  • Mei-Liang Huang,

    Affiliation: National Health Research Institutes (NHRI), Zhunan, Taiwan

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  • Pai-Shan Chiang,

    Affiliation: National Health Research Institutes (NHRI), Zhunan, Taiwan

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  • Min-Yuan Chia,

    Affiliation: National Health Research Institutes (NHRI), Zhunan, Taiwan

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  • Shu-Ting Luo,

    Affiliation: National Health Research Institutes (NHRI), Zhunan, Taiwan

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  • Luan-Yin Chang,

    Affiliation: National Taiwan University Hospital, Taipei, Taiwan

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  • Tzou-Yien Lin,

    Affiliation: Chang Gung Memorial Hospital (CGMH), Taoyuan, Taiwan

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  • Mei-Shang Ho,

    Affiliation: Institute of Biomedical Sciences, Academia Sinica, Taipei, Taiwan

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  • Min-Shi Lee mail

    minshi@nhri.org.tw

    Affiliation: National Health Research Institutes (NHRI), Zhunan, Taiwan

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  • Published: February 14, 2013
  • DOI: 10.1371/journal.pntd.0002067

About the Authors

Mei-Liang Huang, Pai-Shan Chiang, Min-Yuan Chia, Shu-Ting Luo, Min-Shi Lee
National Health Research Institutes (NHRI), Zhunan, Taiwan
Luan-Yin Chang
National Taiwan University Hospital, Taipei, Taiwan
Tzou-Yien Lin
Chang Gung Memorial Hospital (CGMH), Taoyuan, Taiwan
Mei-Shang Ho
Institute of Biomedical Sciences, Academia Sinica, Taipei, Taiwan

Corresponding Author

Email: minshi@nhri.org.tw

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: MSL. Performed the experiments: MLH PSC MYC STL. Analyzed the data: MLH PSC MYC STL. Contributed reagents/materials/analysis tools: LYC TYL MSH. Wrote the paper: MLH MSL.