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Research Article

Rapidly Boosted Plasma IL-5 Induced by Treatment of Human Schistosomiasis haematobium Is Dependent on Antigen Dose, IgE and Eosinophils

  • Shona Wilson mail,

    sw320@cam.ac.uk

    Affiliation: Department of Pathology, University of Cambridge, Cambridge, United Kingdom

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  • Frances M. Jones,

    Affiliation: Department of Pathology, University of Cambridge, Cambridge, United Kingdom

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  • Hassan K. M. Fofana,

    Affiliation: Institut National de Recherche en Santé Publique, Bamako, Mali

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  • Aissata Doucouré,

    Affiliation: Institut National de Recherche en Santé Publique, Bamako, Mali

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  • Aly Landouré,

    Affiliation: Institut National de Recherche en Santé Publique, Bamako, Mali

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  • Gachuhi Kimani,

    Affiliation: Kenya Medical Research Institute, Nairobi, Kenya

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  • Joseph K. Mwatha,

    Affiliation: Kenya Medical Research Institute, Nairobi, Kenya

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  • Moussa Sacko,

    Affiliation: Institut National de Recherche en Santé Publique, Bamako, Mali

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  • Birgitte J. Vennervald,

    Affiliation: DBL – Centre for Health Research and Development, Faculty of Life Sciences, University of Copenhagen, Frederiksberg C, Denmark

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  • David W. Dunne

    Affiliation: Department of Pathology, University of Cambridge, Cambridge, United Kingdom

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  • Published: March 28, 2013
  • DOI: 10.1371/journal.pntd.0002149

About the Authors

Shona Wilson, Frances M. Jones, David W. Dunne
Department of Pathology, University of Cambridge, Cambridge, United Kingdom
Hassan K. M. Fofana, Aissata Doucouré, Aly Landouré, Moussa Sacko
Institut National de Recherche en Santé Publique, Bamako, Mali
Gachuhi Kimani, Joseph K. Mwatha
Kenya Medical Research Institute, Nairobi, Kenya
Birgitte J. Vennervald
DBL – Centre for Health Research and Development, Faculty of Life Sciences, University of Copenhagen, Frederiksberg C, Denmark

Corresponding Author

Email: sw320@cam.ac.uk

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Managed field activities: AL MS. Conceived and designed the experiments: SW AL MS BJV DWD. Performed the experiments: SW FMJ HKMF AD GK JKM. Analyzed the data: SW. Contributed reagents/materials/analysis tools: MS BJV DWD. Wrote the paper: SW DWD.