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Table of Contents: July 2008

COVER

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Nematode Protein Diversity Surveyed

Advanced analytical techniques have permitted the identification of new nematode proteins from a wide survey of genes expressed in human, animal, and plant parasites. These may include novel drug and vaccine targets (see Wasmuth et al. doi:10.1371/journal.pntd.0000258).

Image Credit: Micrograph by Leo Liu, final image by James Wasmuth and Mark Blaxter.

Editorial

Interview

Expert Commentary

Review

The NIH-NIAID Schistosomiasis Resource Center

Fred A. Lewis, Yung-san Liang, Nithya Raghavan, Matty Knight

Research Articles

Landscape Diversity Related to Buruli Ulcer Disease in Côte d'Ivoire

Télesphore Brou, Hélène Broutin, Eric Elguero, Henri Asse, Jean-François Guegan

Acute Schistosoma mansoni Infection Increases Susceptibility to Systemic SHIV Clade C Infection in Rhesus Macaques after Mucosal Virus Exposure

Agnès-Laurence Chenine, Ela Shai-Kobiler, Lisa N. Steele, Helena Ong, Peter Augostini, Ruijiang Song, Sandra J. Lee, Patrick Autissier, Ruth M. Ruprecht, W. Evan Secor

The Interplay between Entamoeba and Enteropathogenic Bacteria Modulates Epithelial Cell Damage

José Manuel Galván-Moroyoqui, M. del Carmen Domínguez-Robles, Elizabeth Franco, Isaura Meza

Proteomic Analysis of Skin Invasion by Blood Fluke Larvae

Elizabeth Hansell, Simon Braschi, Katalin F. Medzihradszky, Mohammed Sajid, Moumita Debnath, Jessica Ingram, K. C. Lim, James H. McKerrow

Relationship between Transmission Intensity and Incidence of Dengue Hemorrhagic Fever in Thailand

Suwich Thammapalo, Yoshiro Nagao, Wataru Sakamoto, Seeviga Saengtharatip, Masaaki Tsujitani, Yasuhide Nakamura, Paul G. Coleman, Clive Davies

Role of Secreted Conjunctival Mucosal Cytokine and Chemokine Proteins in Different Stages of Trachomatous Disease

Troy A. Skwor, Berna Atik, Raj Prasad Kandel, Him Kant Adhikari, Bassant Sharma, Deborah Dean

Development of Functional Genomic Tools in Trematodes: RNA Interference and Luciferase Reporter Gene Activity in Fasciola hepatica

Gabriel Rinaldi, Maria E. Morales, Martín Cancela, Estela Castillo, Paul J. Brindley, José F. Tort

Differentiation and Gene Flow among European Populations of Leishmania infantum MON-1

Katrin Kuhls, Carmen Chicharro, Carmen Cañavate, Sofia Cortes, Lenea Campino, Christos Haralambous, Ketty Soteriadou, Francine Pratlong, Jean-Pierre Dedet, Isabel Mauricio, Michael Miles, Matthias Schaar, Sebastian Ochsenreither, Oliver A. Radtke, Gabriele Schönian

Metabolic Profiling of an Echinostoma caproni Infection in the Mouse for Biomarker Discovery

Jasmina Saric, Jia V. Li, Yulan Wang, Jennifer Keiser, Jake G. Bundy, Elaine Holmes, Jürg Utzinger

On the Extent and Origins of Genic Novelty in the Phylum Nematoda

James Wasmuth, Ralf Schmid, Ann Hedley, Mark Blaxter