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Table of Contents: March 2011

COVER

Cell type-specific markers highlight anatomical details of a Schistosoma mansoni cercaria.

Image Credit: James J. Collins III, Ryan S. King, and Phillip A. Newmark
Issue Image

Maximum projection image showing nuclei (pseudo-colored orange/magenta), musculature (blue), and components of the nervous system (anti-beta-tubulin, gold) as visualized by confocal microscopy. (see Collins et al., 10.1371/journal.pntd.0001009).

Editorial

Viewpoints

Expert Commentary

Policy Platform

Vaccines for the Leishmaniases: Proposals for a Research Agenda

Carlos Henrique Nery Costa, Nathan C. Peters, Sandra Regina Maruyama, Eldo Cardoso de Brito Jr., Isabel Kinney Ferreira de Miranda Santos , The Working Group on Research Priorities for Development of Leishmaniasis Vaccines

Research Articles

Assessment of the Anthelmintic Efficacy of Albendazole in School Children in Seven Countries Where Soil-Transmitted Helminths Are Endemic

Jozef Vercruysse, Jerzy M. Behnke, Marco Albonico, Shaali Makame Ame, Cécile Angebault, Jeffrey M. Bethony, Dirk Engels, Bertrand Guillard, Nguyen Thi Viet Hoa, Gagandeep Kang, Deepthi Kattula, Andrew C. Kotze, James S. McCarthy, Zeleke Mekonnen, Antonio Montresor, Maria Victoria Periago, Laurentine Sumo, Louis-Albert Tchuem Tchuenté, Dang Thi Cam Thach, Ahmed Zeynudin, Bruno Levecke

Evaluation of the Effectiveness of Insecticide Treated Materials for Household Level Dengue Vector Control

Veerle Vanlerberghe, Elci Villegas, Milagros Oviedo, Alberto Baly, Audrey Lenhart, P. J. McCall, Patrick Van der Stuyft

Assessing the Impact of Misclassification Error on an Epidemiological Association between Two Helminthic Infections

Mushfiqur R. Tarafder, Hélène Carabin, Stephen T. McGarvey, Lawrence Joseph, Ernesto Balolong Jr., Remigio Olveda

Dengue in Thailand and Cambodia: An Assessment of the Degree of Underrecognized Disease Burden Based on Reported Cases

Ole Wichmann, In-Kyu Yoon, Sirenda Vong, Kriengsak Limkittikul, Robert V. Gibbons, Mammen P. Mammen, Sowath Ly, Philippe Buchy, Chukiat Sirivichayakul, Rome Buathong, Rekol Huy, G. William Letson, Arunee Sabchareon

Predictors for Abundance of Host Flea and Floor Flea in Households of Villages with Endemic Commensal Rodent Plague, Yunnan Province, China

Jia-Xiang Yin, Alan Geater, Virasakdi Chongsuvivatwong, Xing-Qi Dong, Chun-Hong Du, You-Hong Zhong

Phenotypic Evidence of Emerging Ivermectin Resistance in Onchocerca volvulus

Mike Y. Osei-Atweneboana, Kwablah Awadzi, Simon K. Attah, Daniel A. Boakye, John O. Gyapong, Roger K. Prichard

Trypanosoma cruzi in the Chicken Model: Chagas-Like Heart Disease in the Absence of Parasitism

Antonio R. L. Teixeira, Clever Gomes, Nadjar Nitz, Alessandro O. Sousa, Rozeneide M. Alves, Maria C. Guimaro, Ciro Cordeiro, Francisco M. Bernal, Ana C. Rosa, Jiri Hejnar, Eduardo Leonardecz, Mariana M. Hecht

Multi-Disease Data Management System Platform for Vector-Borne Diseases

Lars Eisen, Marlize Coleman, Saul Lozano-Fuentes, Nathan McEachen, Miguel Orlans, Michael Coleman

Risk Factors for Ocular Infection with Chlamydia trachomatis in Children 6 Months following Mass Treatment in Tanzania

Luis Carlos Cajas-Monson, Harran Mkocha, Beatriz Muñoz, Thomas C. Quinn, Charlotte A. Gaydos, Sheila K. West

BCG-Mediated Protection against Mycobacterium ulcerans Infection in the Mouse

Paul J. Converse, Deepak V. Almeida, Eric L. Nuermberger, Jacques H. Grosset

Correlation of Clinical Trachoma and Infection in Aboriginal Communities

Claude-Edouard C. Michel, Katrina G. Roper, Magda A. Divena, Helen H. Lee, Hugh R. Taylor

Towards a Semen Proteome of the Dengue Vector Mosquito: Protein Identification and Potential Functions

Laura K. Sirot, Melissa C. Hardstone, Michelle E. H. Helinski, José M. C. Ribeiro, Mari Kimura, Prasit Deewatthanawong, Mariana F. Wolfner, Laura C. Harrington

Evaluation of a 25-Year-Program for the Control of Schistosomiasis Mansoni in an Endemic Area in Brazil

Ana K. Sarvel, Áureo A. Oliveira, Alexandre R. Silva, Anna C. L. Lima, Naftale Katz

Leprosy among Patient Contacts: A Multilevel Study of Risk Factors

Anna M. Sales, Antonio Ponce de Leon, Nádia C. Düppre, Mariana A. Hacker, José Augusto C. Nery, Euzenir N. Sarno, Maria L. F. Penna

Genetic and Functional Role of TNF-alpha in the Development Trypanosoma cruzi Infection

Cristina Wide Pissetti, Dalmo Correia, Rafael Faria de Oliveira, Maurício Manoel Llaguno, Marly Aparecida Spadotto Balarin, Roseane Lopes Silva-Grecco, Virmondes Rodrigues Jr

Analysis of Antibody and Cytokine Markers for Leprosy Nerve Damage and Reactions in the INFIR Cohort in India

Rupendra Jadhav, Lavanya Suneetha, Ravindra Kamble, Vidyagouri Shinde, Karuna Devi, Meher Vani Chaduvula, Renuka Raju, Sujai Suneetha, Peter G. Nicholls, Wim H. van Brakel, Diana N. J. Lockwood

Incremental Cost of Conducting Population-Based Prevalence Surveys for a Neglected Tropical Disease: The Example of Trachoma in 8 National Programs

Chaoqun Chen, Elizabeth A. Cromwell, Jonathan D. King, Aryc Mosher, Emma M. Harding-Esch, Jeremiah M. Ngondi, Paul M. Emerson

Mucosal Leishmaniasis Caused by Leishmania (Viannia) braziliensis and Leishmania (Viannia) guyanensis in the Brazilian Amazon

Jorge Augusto de Oliveira Guerra, Suzane Ribeiro Prestes, Henrique Silveira, Leila Inês de Aguiar Raposo Câmara Coelho, Pricila Gama, Aristoteles Moura, Valdir Amato, Maria das Graças Vale Barbosa, Luiz Carlos de Lima Ferreira

Neuropathic Pain and Psychological Morbidity in Patients with Treated Leprosy: A Cross-Sectional Prevalence Study in Mumbai

Estrella Lasry-Levy, Aki Hietaharju, Vivek Pai, Ramaswamy Ganapati, Andrew S. C. Rice, Maija Haanpää, Diana N. J. Lockwood

Co-Administration of a Plasmid DNA Encoding IL-15 Improves Long-Term Protection of a Genetic Vaccine against Trypanosoma cruzi

Christopher S. Eickhoff, Jose R. Vasconcelos, Nicole L. Sullivan, Azra Blazevic, Oscar Bruna-Romero, Mauricio M. Rodrigues, Daniel F. Hoft

Shotgun Sequencing Analysis of Trypanosoma cruzi I Sylvio X10/1 and Comparison with T. cruzi VI CL Brener

Oscar Franzén, Stephen Ochaya, Ellen Sherwood, Michael D. Lewis, Martin S. Llewellyn, Michael A. Miles, Björn Andersson

Evaluation of Mammalian and Intermediate Host Surveillance Methods for Detecting Schistosomiasis Reemergence in Southwest China

Elizabeth J. Carlton, Michael N. Bates, Bo Zhong, Edmund Y. W. Seto, Robert C. Spear

An Atlas for Schistosoma mansoni Organs and Life-Cycle Stages Using Cell Type-Specific Markers and Confocal Microscopy

James J. Collins III, Ryan S. King, Alexis Cogswell, David L. Williams, Phillip A. Newmark

BALB/c Mice Infected with Antimony Treatment Refractory Isolate of Leishmania braziliensis Present Severe Lesions due to IL-4 Production

Diego L. Costa, Vanessa Carregaro, Djalma S. Lima-Júnior, Neide M. Silva, Cristiane M. Milanezi, Cristina R. Cardoso, Ângela Giudice, Amélia R. de Jesus, Edgar M. Carvalho, Roque P. Almeida, João S. Silva

Immunological and Viral Determinants of Dengue Severity in Hospitalized Adults in Ha Noi, Viet Nam

Annette Fox, Le Nguyen Minh Hoa, Cameron P. Simmons, Marcel Wolbers, Heiman F. L. Wertheim, Pham Thi Khuong, Tran Thi Hai Ninh, Trinh Thi Minh Lien, Nguyen Thi Lien, Nguyen Vu Trung, Nguyen Duc Hien, Jeremy Farrar, Peter Horby, Walter R. Taylor, Nguyen Van Kinh

Clinical Presentation of T.b. rhodesiense Sleeping Sickness in Second Stage Patients from Tanzania and Uganda

Irene Kuepfer, Emma Peter Hhary, Mpairwe Allan, Andrew Edielu, Christian Burri, Johannes A. Blum

Prevalence and Risk Factors of Intestinal Parasitism in Rural and Remote West Malaysia

Romano Ngui, Saidon Ishak, Chow Sek Chuen, Rohela Mahmud, Yvonne A. L. Lim

Determinants of Inapparent and Symptomatic Dengue Infection in a Prospective Study of Primary School Children in Kamphaeng Phet, Thailand

Timothy P. Endy, Kathryn B. Anderson, Ananda Nisalak, In-Kyu Yoon, Sharone Green, Alan L. Rothman, Stephen J. Thomas, Richard G. Jarman, Daniel H. Libraty, Robert V. Gibbons