Schistosoma mansoni Diagnosis Pre- and Post-Repeated-Praziquantel Treatment.
Kato-Katz thick smears and urine point-of care circulating cathodic antigen tests (POC-CCA) for the diagnosis of Schistosoma mansoni infections in primary school children in Uganda. Whilst Kato-Katz thick smears enable the concurrent diagnosis and quantification of soil transmitted helminthiases, POC-CCA can only detect (intestinal) schistosomiasis infections. However, POC-CCA are rapid, more culturally acceptable and have a higher sensitivity as infection intensities decrease with on-going mass drug administration. See Lamberton et al.
Image Credit: Poppy Lamberton