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Table of Contents: November 2009

Issue Image

Cattle that graze near the River Vina du Sud in northern Cameroon naturally acquire the filarial parasite Onchocerca ochengi, the closest relative of O. volvulus, which causes river blindness in humans. In this issue, Makepeace et al. (doi:10.1371/journal.pntd.0000544) find that animals vaccinated with a combination of eight recombinant antigens were partially protected against patent infection after nearly two years of field exposure.

Photo Credit: Kevin Krcmarik

Editorial

Viewpoints

From Innovation to Application

Improved Models of Mini Anion Exchange Centrifugation Technique (mAECT) and Modified Single Centrifugation (MSC) for Sleeping Sickness Diagnosis and Staging

Philippe Büscher, Dieudonné Mumba Ngoyi, Jacques Kaboré, Veerle Lejon, Jo Robays, Vincent Jamonneau, Nicolas Bebronne, Wim Van der Veken, Sylvain Biéler

Research Articles

Characterizing the Aedes aegypti Population in a Vietnamese Village in Preparation for a Wolbachia-Based Mosquito Control Strategy to Eliminate Dengue

Jason A. L. Jeffery, Nguyen Thi Yen, Vu Sinh Nam, Le Trung Nghia, Ary A. Hoffmann, Brian H. Kay, Peter A. Ryan

Mycolactone Gene Expression Is Controlled by Strong SigA-Like Promoters with Utility in Studies of Mycobacterium ulcerans and Buruli Ulcer

Nicholas J. Tobias, Torsten Seemann, Sacha J. Pidot, Jessica L. Porter, Laurent Marsollier, Estelle Marion, Franck Letournel, Tasnim Zakir, Joseph Azuolas, John R. Wallace, Hui Hong, John K. Davies, Benjamin P. Howden, Paul D. R. Johnson, Grant A. Jenkin, Timothy P. Stinear

A Regional Initiative to Reduce Skin Infections amongst Aboriginal Children Living in Remote Communities of the Northern Territory, Australia

Ross M. Andrews, Therese Kearns, Christine Connors, Colin Parker, Kylie Carville, Bart J. Currie, Jonathan R. Carapetis

Seroprevalence to the Antigens of Taenia solium Cysticercosis among Residents of Three Villages in Burkina Faso: A Cross-Sectional Study

Hélène Carabin, Athanase Millogo, Nicolas Praet, Sennen Hounton, Zékiba Tarnagda, Rasmané Ganaba, Pierre Dorny, Pascal Nitiéma, Linda D. Cowan , Évaluation du Fardeau Économique de la Cysticercose Au Burkina Faso (ÉFÉCAB)

Prevalence and Risk Factors of Lassa Seropositivity in Inhabitants of the Forest Region of Guinea: A Cross-Sectional Study

Solen Kernéis, Lamine Koivogui, N'Faly Magassouba, Kekoura Koulemou, Rosamund Lewis, Aristide Aplogan, Rebecca F. Grais, Philippe J. Guerin, Elisabeth Fichet-Calvet

An ex-vivo Human Intestinal Model to Study Entamoeba histolytica Pathogenesis

Devendra Bansal, Patrick Ave, Sophie Kerneis, Pascal Frileux, Olivier Boché, Anne Catherine Baglin, Geneviève Dubost, Anne-Sophie Leguern, Marie-Christine Prevost, Rivka Bracha, David Mirelman, Nancy Guillén, Elisabeth Labruyère

Immunisation with a Multivalent, Subunit Vaccine Reduces Patent Infection in a Natural Bovine Model of Onchocerciasis during Intense Field Exposure

Benjamin L. Makepeace, Siv Aina Jensen, Sandra J. Laney, Charles K. Nfon, Leo M. Njongmeta, Vincent N. Tanya, Steven A. Williams, Albert E. Bianco, Alexander J. Trees

Spatial Evaluation and Modeling of Dengue Seroprevalence and Vector Density in Rio de Janeiro, Brazil

Nildimar Alves Honório, Rita Maria Ribeiro Nogueira, Cláudia Torres Codeço, Marilia Sá Carvalho, Oswaldo Gonçalves Cruz, Mônica de Avelar Figueiredo Mafra Magalhães, Josélio Maria Galvão de Araújo, Eliane Saraiva Machado de Araújo, Marcelo Quintela Gomes, Luciane Silva Pinheiro, Célio da Silva Pinel, Ricardo Lourenço-de-Oliveira

Molecular Characterization of the Schistosoma mansoni Zinc Finger Protein SmZF1 as a Transcription Factor

Marcela G. Drummond, Carlos E. Calzavara-Silva, Diego S. D'Astolfo, Fernanda C. Cardoso, Matheus A. Rajão, Marina M. Mourão, Elisandra Gava, Sérgio C. Oliveira, Andréa M. Macedo, Carlos R. Machado, Sérgio D. J. Pena, Gregory T. Kitten, Glória R. Franco

Identification of Potent Chemotypes Targeting Leishmania major Using a High-Throughput, Low-Stringency, Computationally Enhanced, Small Molecule Screen

Elizabeth R. Sharlow, David Close, Tongying Shun, Stephanie Leimgruber, Robyn Reed, Gabriela Mustata, Peter Wipf, Jacob Johnson, Michael O'Neil, Max Grögl, Alan J. Magill, John S. Lazo

Development of a Mouse Monoclonal Antibody Cocktail for Post-exposure Rabies Prophylaxis in Humans

Thomas Müller, Bernhard Dietzschold, Hildegund Ertl, Anthony R. Fooks, Conrad Freuling, Christine Fehlner-Gardiner, Jeannette Kliemt, Francois X. Meslin, Charles E. Rupprecht, Noël Tordo, Alexander I. Wanderler, Marie Paule Kieny

Anti-schistosomal Intervention Targets Identified by Lifecycle Transcriptomic Analyses

Jennifer M. Fitzpatrick, Emily Peak, Samirah Perally, Iain W. Chalmers, John Barrett, Timothy P. Yoshino, Alasdair C. Ivens, Karl F. Hoffmann