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Table of Contents | April 2009

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Unique microtubular assemblies in Entamoeba histolytica.

Most organisms segregate their duplicated genome copies on bipolar microtubular spindles. E. histolytica nuclei often accumulate multiple copies of the genome. This micrograph shows multi-polar microtubular spindles where genome segregation likely occurs in E. histolytica cells (see Mukherjee et al., doi:10.1371/journal.pntd.0000409).

Image Credit: Shubhra Majumder, Bose Institute

 
 

Editorial

One World Health: Neglected Tropical Diseases in a Flat World

Peter J. Hotez

 

Viewpoints

Conducting Research in Disease Outbreaks

Ruth Macklin, Ethan Cowan

Introduction of Dengue Virus 4 (DENV-4) Genotype I into Brazil from Asia?

Fernando Lucas de Melo, Camila Malta Romano, Paolo Marinho de Andrade Zanotto

 

Review

Use of Mapping and Spatial and Space-Time Modeling Approaches in Operational Control of Aedes aegypti and Dengue

Lars Eisen, Saul Lozano-Fuentes

 

Research Articles

Development and Evaluation of Two Simple, Rapid Immunochromatographic Tests for the Detection of Yersinia pestis Antibodies in Humans and Reservoirs

Minoarisoa Rajerison, Sylvie Dartevelle, Lalao A. Ralafiarisoa, Idir Bitam, Dinh Thi Ngoc Tuyet, Voahangy Andrianaivoarimanana, Faridabano Nato, Lila Rahalison

Author Summary

Dengue Virus Serotype 2 from a Sylvatic Lineage Isolated from a Patient with Dengue Hemorrhagic Fever

Jane Cardosa, Mong How Ooi, Phaik Hooi Tio, David Perera, Edward C. Holmes, Khatijar Bibi, Zahara Abdul Manap

Author Summary

Echinococcus granulosus Infection and Options for Control of Cystic Echinococcosis in Tibetan Communities of Western Sichuan Province, China

Yu Rong Yang, Donald P. McManus, Yan Huang, David D. Heath

Author Summary

Effects of a Five-Year Citywide Intervention Program To Control Aedes aegypti and Prevent Dengue Outbreaks in Northern Argentina

Ricardo E. Gürtler, Fernando M. Garelli, Héctor D. Coto

Author Summary

Marriage, Sex, and Hydrocele: An Ethnographic Study on the Effect of Filarial Hydrocele on Conjugal Life and Marriageability from Orissa, India

Bontha V. Babu, Suchismita Mishra, Abhaya N. Nayak

Author Summary

A Kernel for Open Source Drug Discovery in Tropical Diseases

Leticia Ortí, Rodrigo J. Carbajo, Ursula Pieper, Narayanan Eswar, Stephen M. Maurer, Arti K. Rai, Ginger Taylor, Matthew H. Todd, Antonio Pineda-Lucena, Andrej Sali, Marc A. Marti-Renom

Author Summary

Accurate Real-Time PCR Strategy for Monitoring Bloodstream Parasitic Loads in Chagas Disease Patients

Tomas Duffy, Margarita Bisio, Jaime Altcheh, Juan Miguel Burgos, Mirta Diez, Mariano Jorge Levin, Roberto Rene Favaloro, Hector Freilij, Alejandro Gabriel Schijman

Author Summary

Filarial Lymphedema Is Characterized by Antigen-Specific Th1 and Th17 Proinflammatory Responses and a Lack of Regulatory T Cells

Subash Babu, Sajid Q. Bhat, N. Pavan Kumar, Angelo B. Lipira, Sanath Kumar, C. Karthik, V. Kumaraswami, Thomas B. Nutman

Author Summary

Diagnosing Schistosomiasis by Detection of Cell-Free Parasite DNA in Human Plasma

Dominic Wichmann, Marcus Panning, Thomas Quack, Stefanie Kramme, Gerd-Dieter Burchard, Christoph Grevelding, Christian Drosten

Author Summary

Gene Flow, Subspecies Composition, and Dengue Virus-2 Susceptibility among Aedes aegypti Collections in Senegal

Massamba Sylla, Christopher Bosio, Ludmel Urdaneta-Marquez, Mady Ndiaye, William C. Black IV

Author Summary

Proteomic Comparison of Entamoeba histolytica and Entamoeba dispar and the Role of E. histolytica Alcohol Dehydrogenase 3 in Virulence

Paul H. Davis, Minghe Chen, Xiaochun Zhang, C. Graham Clark, R. Reid Townsend, Samuel L. Stanley Jr.

Author Summary

Optimization of Control Strategies for Non-Domiciliated Triatoma dimidiata, Chagas Disease Vector in the Yucatán Peninsula, Mexico

Corentin Barbu, Eric Dumonteil, Sébastien Gourbière

Author Summary

Phenotypic and Functional Characterization of Human Memory T Cell Responses to Burkholderia pseudomallei

Patcharaporn Tippayawat, Wipawee Saenwongsa, Jirawan Mahawantung, Duangchan Suwannasaen, Ploenchan Chetchotisakd, Direk Limmathurotsakul, Sharon J. Peacock, Philip L. Felgner, Helen S. Atkins, Richard W. Titball, Gregory J. Bancroft, Ganjana Lertmemongkolchai

Author Summary

Inter-Cellular Variation in DNA Content of Entamoeba histolytica Originates from Temporal and Spatial Uncoupling of Cytokinesis from the Nuclear Cycle

Chandrama Mukherjee, Shubhra Majumder, Anuradha Lohia

Author Summary

Brugia malayi Excreted/Secreted Proteins at the Host/Parasite Interface: Stage- and Gender-Specific Proteomic Profiling

Sasisekhar Bennuru, Roshanak Semnani, Zhaojing Meng, Jose M. C. Ribeiro, Timothy D. Veenstra, Thomas B. Nutman

Author Summary

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