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Issue Image August

2010

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Red fluorescence of two transgenic Aedes albopictus larvae.

Both larvae carry an attP docking site integrated into the genome via piggyBac-mediated germline transformation using a cyan fluorescent marker (see article by Labbé et al., doi:10.1371/journal.pntd.0000788). The top larva also carries a 3xP3-DsRed2 marker—leading to expression of DsRed2 red fluorescent protein and hence prominent red fluorescence in the eyes and optic nerve—integrated into the attP site via PhiC31-mediated site-specific integration. Development of gene transfer technology for Aedes albopictus is a key step in the study and control of this invasive species using novel molecular techniques and genetic control strategies.

Image Credit: Geneviève Labbé/Oxitec Ltd.

 

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