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Research Article

Human TLR1 Deficiency Is Associated with Impaired Mycobacterial Signaling and Protection from Leprosy Reversal Reaction

  • Elizabeth A. Misch,

    Affiliation: University of Washington School of Medicine, Seattle, Washington, United States of America

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  • Murdo Macdonald,

    Affiliation: Mycobacterial Research Laboratory, Anandaban Hospital, Kathmandu, Nepal

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  • Chaman Ranjit,

    Affiliation: Mycobacterial Research Laboratory, Anandaban Hospital, Kathmandu, Nepal

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  • Bishwa R. Sapkota,

    Affiliation: Mycobacterial Research Laboratory, Anandaban Hospital, Kathmandu, Nepal

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  • Richard D. Wells,

    Affiliation: University of Washington School of Medicine, Seattle, Washington, United States of America

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  • M. Ruby Siddiqui,

    Affiliation: Laboratory of Mycobacterial Immunity and Pathogenesis, Public Health Research Institute at the University of Medicine and Dentistry of New Jersey, Newark, New Jersey, United States of America

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  • Gilla Kaplan,

    Affiliation: Laboratory of Mycobacterial Immunity and Pathogenesis, Public Health Research Institute at the University of Medicine and Dentistry of New Jersey, Newark, New Jersey, United States of America

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  • Thomas R. Hawn mail

    thawn@u.washington.edu

    Affiliation: University of Washington School of Medicine, Seattle, Washington, United States of America

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  • Published: May 07, 2008
  • DOI: 10.1371/journal.pntd.0000231

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