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Research Article

Filarial Lymphedema Is Characterized by Antigen-Specific Th1 and Th17 Proinflammatory Responses and a Lack of Regulatory T Cells

  • Subash Babu mail,

    sbabu@mail.nih.gov

    Affiliations: National Institutes of Health–International Center for Excellence in Research, Chennai, India, SAIC–Frederick, Inc., NCI-Frederick, Frederick, Maryland, United States of America

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  • Sajid Q. Bhat,

    Affiliation: National Institutes of Health–International Center for Excellence in Research, Chennai, India

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  • N. Pavan Kumar,

    Affiliation: National Institutes of Health–International Center for Excellence in Research, Chennai, India

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  • Angelo B. Lipira,

    Affiliation: National Institutes of Health–International Center for Excellence in Research, Chennai, India

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  • Sanath Kumar,

    Affiliation: National Institutes of Health–International Center for Excellence in Research, Chennai, India

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  • C. Karthik,

    Affiliation: National Institutes of Health–International Center for Excellence in Research, Chennai, India

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  • V. Kumaraswami,

    Affiliations: National Institutes of Health–International Center for Excellence in Research, Chennai, India, Tuberculosis Research Center, Chennai, India

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  • Thomas B. Nutman

    Affiliation: Laboratory of Parasitic Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, United States of America

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  • Published: April 21, 2009
  • DOI: 10.1371/journal.pntd.0000420

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