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Research Article

Untargeted Metabolomics Reveals a Lack Of Synergy between Nifurtimox and Eflornithine against Trypanosoma brucei

  • Isabel M. Vincent,

    Affiliation: The Wellcome Trust Centre for Molecular Parasitology, Institute for Infection, Immunity and Inflammation, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, United Kingdom

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  • Darren J. Creek,

    Affiliations: The Wellcome Trust Centre for Molecular Parasitology, Institute for Infection, Immunity and Inflammation, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, United Kingdom, Glasgow Polyomics Facility, University of Glasgow, Glasgow, United Kingdom

    X
  • Karl Burgess,

    Affiliations: The Wellcome Trust Centre for Molecular Parasitology, Institute for Infection, Immunity and Inflammation, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, United Kingdom, Glasgow Polyomics Facility, University of Glasgow, Glasgow, United Kingdom

    X
  • Debra J. Woods,

    Affiliation: Pfizer Animal Health, Pfizer Inc, Kalamazoo, Michigan, United States of America

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  • Richard J. S. Burchmore,

    Affiliations: The Wellcome Trust Centre for Molecular Parasitology, Institute for Infection, Immunity and Inflammation, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, United Kingdom, Glasgow Polyomics Facility, University of Glasgow, Glasgow, United Kingdom

    X
  • Michael P. Barrett mail

    michael.barrett@glasgow.ac.uk

    Affiliations: The Wellcome Trust Centre for Molecular Parasitology, Institute for Infection, Immunity and Inflammation, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, United Kingdom, Glasgow Polyomics Facility, University of Glasgow, Glasgow, United Kingdom

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  • Published: May 01, 2012
  • DOI: 10.1371/journal.pntd.0001618

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