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Research Article

Elevated Plasma IL-6 Associates with Increased Risk of Advanced Fibrosis and Cholangiocarcinoma in Individuals Infected by Opisthorchis viverrini

  • Banchob Sripa,

    Affiliation: Department of Pathology, Khon Kaen University School of Medicine, Khon Kaen, Thailand

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  • Bandit Thinkhamrop,

    Affiliation: Department of Epidemiology and Biostatistics, Khon Kaen University School of Public Health, Khon Kaen, Thailand

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  • Eimorn Mairiang,

    Affiliation: Department of Radiology, Khon Kaen University School of Medicine, Khon Kaen, Thailand

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  • Thewarach Laha,

    Affiliation: Department of Parasitology, Khon Kaen University School of Medicine, Khon Kaen, Thailand

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  • Sasithorn Kaewkes,

    Affiliation: Department of Parasitology, Khon Kaen University School of Medicine, Khon Kaen, Thailand

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  • Paiboon Sithithaworn,

    Affiliation: Department of Parasitology, Khon Kaen University School of Medicine, Khon Kaen, Thailand

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  • Maria Victoria Periago,

    Affiliation: Instituto René Rachou, Belo Horizonte, Minas Gerais, Brazil

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  • Vajarabhongsa Bhudhisawasdi,

    Affiliations: Department of Surgery, Khon Kaen University School of Medicine, Khon Kaen, Thailand, Liver Fluke and Cholangiocarcinoma Research Center, Khon Kaen University, Khon Kaen, Thailand

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  • Ponlapat Yonglitthipagon,

    Affiliations: Department of Pathology, Khon Kaen University School of Medicine, Khon Kaen, Thailand, Queensland Tropical Health Alliance, James Cook University, Cairns, Queensland, Australia

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  • Jason Mulvenna,

    Affiliation: Queensland Tropical Health Alliance, James Cook University, Cairns, Queensland, Australia

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  • Paul J. Brindley,

    Affiliation: Department of Microbiology, Immunology & Tropical Medicine, George Washington University Medical Center, Washington, D. C., United States of America

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  • Alex Loukas,

    Affiliation: Queensland Tropical Health Alliance, James Cook University, Cairns, Queensland, Australia

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  • Jeffrey M. Bethony mail

    jbethony@email.gwu.edu

    Affiliations: Instituto René Rachou, Belo Horizonte, Minas Gerais, Brazil, Department of Microbiology, Immunology & Tropical Medicine, George Washington University Medical Center, Washington, D. C., United States of America

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  • Published: May 22, 2012
  • DOI: 10.1371/journal.pntd.0001654

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