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Research Article

Identification of Compounds with Anti-Proliferative Activity against Trypanosoma brucei brucei Strain 427 by a Whole Cell Viability Based HTS Campaign

  • Melissa L. Sykes equal contributor,

    equal contributor Contributed equally to this work with: Melissa L. Sykes, Jonathan B. Baell

    Affiliation: Discovery Biology, Eskitis Institute for Cell and Molecular Therapies, Griffith University, Nathan, Queensland, Australia

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  • Jonathan B. Baell equal contributor,

    equal contributor Contributed equally to this work with: Melissa L. Sykes, Jonathan B. Baell

    Affiliations: The Walter and Eliza Hall Institute of Medical Research, Parkville, Victoria, Australia, Department of Medical Biology, The University of Melbourne, Parkville, Victoria, Australia, Department of Medicinal Chemistry, Faculty of Pharmacy and Pharmaceutical Sciences, Monash Institute of Pharmaceutical Sciences, Monash University, Parkville, Victoria, Australia

    X
  • Marcel Kaiser,

    Affiliations: Swiss Tropical and Public Health Institute, Basel, Switzerland, University of Basel, Basel, Switzerland

    X
  • Eric Chatelain,

    Affiliation: Drugs for Neglected Diseases initiative (DNDi), Geneva, Switzerland

    X
  • Sarah R. Moawad,

    Affiliations: The Walter and Eliza Hall Institute of Medical Research, Parkville, Victoria, Australia, Department of Medical Biology, The University of Melbourne, Parkville, Victoria, Australia

    X
  • Danny Ganame,

    Affiliations: The Walter and Eliza Hall Institute of Medical Research, Parkville, Victoria, Australia, Department of Medical Biology, The University of Melbourne, Parkville, Victoria, Australia

    X
  • Jean-Robert Ioset,

    Affiliation: Drugs for Neglected Diseases initiative (DNDi), Geneva, Switzerland

    X
  • Vicky M. Avery mail

    v.avery@griffith.edu.au

    Affiliation: Discovery Biology, Eskitis Institute for Cell and Molecular Therapies, Griffith University, Nathan, Queensland, Australia

    X
  • Published: November 29, 2012
  • DOI: 10.1371/journal.pntd.0001896

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