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Research Article

A Single Immunization with MVA Expressing GnGc Glycoproteins Promotes Epitope-specific CD8+-T Cell Activation and Protects Immune-competent Mice against a Lethal RVFV Infection

  • Elena López-Gil,

    Affiliation: Centro de Investigación en Sanidad Animal, INIA, Valdeolmos, Madrid, Spain

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  • Gema Lorenzo,

    Affiliation: Centro de Investigación en Sanidad Animal, INIA, Valdeolmos, Madrid, Spain

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  • Esther Hevia,

    Affiliation: Centro de Investigación en Sanidad Animal, INIA, Valdeolmos, Madrid, Spain

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  • Belén Borrego,

    Affiliation: Centro de Investigación en Sanidad Animal, INIA, Valdeolmos, Madrid, Spain

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  • Martin Eiden,

    Affiliation: Friedrich-Loeffler-Institut, Federal Research Institute for Animal Health, Greifswald-Insel Riems, Germany

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  • Martin Groschup,

    Affiliation: Friedrich-Loeffler-Institut, Federal Research Institute for Animal Health, Greifswald-Insel Riems, Germany

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  • Sarah C. Gilbert,

    Affiliation: Jenner Institute, University of Oxford, Oxford, United Kingdom

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  • Alejandro Brun mail

    brun@inia.es

    Affiliation: Centro de Investigación en Sanidad Animal, INIA, Valdeolmos, Madrid, Spain

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  • Published: July 11, 2013
  • DOI: 10.1371/journal.pntd.0002309

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