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Issue Image

PLoS Neglected Tropical Diseases Issue Image | Vol. 3(8) August 2009

<b>RNAi-altered gene expression in larval schistosomes.</b>

Confocal fluorescence micrograph of two in vitro-derived primary sporocysts of Schistosoma mansoni showing the somatic distribution of immunoreactive elongation factor 1a (EF1a) protein (green). Larvae are counterstained for actin (red) and DNA (blue) using Alexa-phalloidin and Hoechst dye, respectively. EF1a was one of 32 genes selected for larval phenotypic profiling by RNA interference (see article by de Moraes Mourão, et al. doi:10.1371/journal.pntd.0000502).

Image Credit: M. de Moraes Mourão, N. Dinguirard. Image was captured using a Nikon Eclipse TE2000 epifluorescent microscope equipped with a Bio-Rad Radiance 2100 MP Rainbow confocal imaging system (Keck Laboratory for Biological Imaging, University of Wisconsin).

RNAi-altered gene expression in larval schistosomes.  Top

Confocal fluorescence micrograph of two in vitro-derived primary sporocysts of Schistosoma mansoni showing the somatic distribution of immunoreactive elongation factor 1a (EF1a) protein (green). Larvae are counterstained for actin (red) and DNA (blue) using Alexa-phalloidin and Hoechst dye, respectively. EF1a was one of 32 genes selected for larval phenotypic profiling by RNA interference (see article by de Moraes Mourão, et al. doi:10.1371/journal.pntd.0000502).

Image Credit: M. de Moraes Mourão, N. Dinguirard. Image was captured using a Nikon Eclipse TE2000 epifluorescent microscope equipped with a Bio-Rad Radiance 2100 MP Rainbow confocal imaging system (Keck Laboratory for Biological Imaging, University of Wisconsin).

Citation: (2009) PLoS Neglected Tropical Diseases Issue Image | Vol. 3(8) August 2009. PLoS Negl Trop Dis 3(8): ev03.i08. doi:10.1371/image.pntd.v03.i08

Published: August 25, 2009

Copyright: © 2009 de Moraes Mourão, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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RNAi-altered gene expression in larval schistosomes.

Confocal fluorescence micrograph of two in vitro-derived primary sporocysts of Schistosoma mansoni showing the somatic distribution of immunoreactive elongation factor 1a (EF1a) protein (green). Larvae are counterstained for actin (red) and DNA (blue) using Alexa-phalloidin and Hoechst dye, respectively. EF1a was one of 32 genes selected for larval phenotypic profiling by RNA interference (see article by de Moraes Mourão, et al. doi:10.1371/journal.pntd.0000502).

Image Credit: M. de Moraes Mourão, N. Dinguirard. Image was captured using a Nikon Eclipse TE2000 epifluorescent microscope equipped with a Bio-Rad Radiance 2100 MP Rainbow confocal imaging system (Keck Laboratory for Biological Imaging, University of Wisconsin).

doi:10.1371/image.pntd.v03.i08.g001
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