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Issue Image

PLoS Neglected Tropical Diseases Issue Image | Vol. 4(8) August 2010

Red fluorescence of two transgenic Aedes albopictus larvae.Both larvae carry an attP docking site integrated into the genome via piggyBac-mediated germline transformation using a cyan fluorescent marker (see article by Labbé et al., doi:10.1371/journal.pntd.0000788). The top larva also carries a 3xP3-DsRed2 marker—leading to expression of DsRed2 red fluorescent protein and hence prominent red fluorescence in the eyes and optic nerve—integrated into the attP site via PhiC31-mediated site-specific integration. Development of gene transfer technology for Aedes albopictus is a key step in the study and control of this invasive species using novel molecular techniques and genetic control strategies. Image Credit: Geneviève Labbé/Oxitec Ltd.

Red fluorescence of two transgenic Aedes albopictus larvae. Top

Both larvae carry an attP docking site integrated into the genome via piggyBac-mediated germline transformation using a cyan fluorescent marker (see article by Labbé et al., doi:10.1371/journal.pntd.0000788). The top larva also carries a 3xP3-DsRed2 marker—leading to expression of DsRed2 red fluorescent protein and hence prominent red fluorescence in the eyes and optic nerve—integrated into the attP site via PhiC31-mediated site-specific integration. Development of gene transfer technology for Aedes albopictus is a key step in the study and control of this invasive species using novel molecular techniques and genetic control strategies.

Image Credit: Geneviève Labbé/Oxitec Ltd.

Citation: (2010) PLoS Neglected Tropical Diseases Issue Image | Vol. 4(8) August 2010. PLoS Negl Trop Dis 4(8): ev04.i08. doi:10.1371/image.pntd.v04.i08

Published: August 31, 2010

Copyright: © 2010 Labbé et al.. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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Red fluorescence of two transgenic Aedes albopictus larvae.

Both larvae carry an attP docking site integrated into the genome via piggyBac-mediated germline transformation using a cyan fluorescent marker (see article by Labbé et al., doi:10.1371/journal.pntd.0000788). The top larva also carries a 3xP3-DsRed2 marker—leading to expression of DsRed2 red fluorescent protein and hence prominent red fluorescence in the eyes and optic nerve—integrated into the attP site via PhiC31-mediated site-specific integration. Development of gene transfer technology for Aedes albopictus is a key step in the study and control of this invasive species using novel molecular techniques and genetic control strategies.

Image Credit: Geneviève Labbé/Oxitec Ltd.

doi:10.1371/image.pntd.v04.i08.g001
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