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Research Article

Mycolactone Diffuses from Mycobacterium ulcerans–Infected Tissues and Targets Mononuclear Cells in Peripheral Blood and Lymphoid Organs

  • Hui Hong,

    Affiliation: University of Cambridge, Department of Biochemistry, Cambridge, United Kingdom

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  • Emmanuelle Coutanceau,

    Affiliation: Institut Pasteur, UP Pathogénomique Mycobactérienne Intégrée, Paris, France

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  • Marion Leclerc,

    Affiliation: Institut Pasteur, UP Pathogénomique Mycobactérienne Intégrée, Paris, France

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  • Laxmee Caleechurn,

    Affiliation: Institut Pasteur, UP Pathogénomique Mycobactérienne Intégrée, Paris, France

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  • Peter F. Leadlay,

    Affiliation: University of Cambridge, Department of Biochemistry, Cambridge, United Kingdom

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  • Caroline Demangel mail

    demangel@pasteur.fr

    Affiliation: Institut Pasteur, UP Pathogénomique Mycobactérienne Intégrée, Paris, France

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  • Published: October 22, 2008
  • DOI: 10.1371/journal.pntd.0000325

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