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Research Article

RNA Interference in Schistosoma mansoni Schistosomula: Selectivity, Sensitivity and Operation for Larger-Scale Screening

  • Saša Štefanić equal contributor,

    equal contributor Contributed equally to this work with: Saša Štefanić, Jan Dvořák

    Affiliation: Sandler Center for Drug Discovery, California Institute for Quantitative Biosciences (QB3), University of California San Francisco, San Francisco, California, United States of America

    Current address: Institute of Parasitology, University of Zurich, Zurich, Switzerland

    X
  • Jan Dvořák equal contributor,

    equal contributor Contributed equally to this work with: Saša Štefanić, Jan Dvořák

    Affiliation: Sandler Center for Drug Discovery, California Institute for Quantitative Biosciences (QB3), University of California San Francisco, San Francisco, California, United States of America

    Current address: Institute of Parasitology, Biology Centre, Academy of Sciences of the Czech Republic, České Budějovice Czech Republic

    X
  • Martin Horn,

    Affiliation: Institute of Organic Chemistry and Biochemistry, Academy of Sciences of the Czech Republic, Praha, Czech Republic

    X
  • Simon Braschi,

    Affiliation: Sandler Center for Drug Discovery, California Institute for Quantitative Biosciences (QB3), University of California San Francisco, San Francisco, California, United States of America

    Current address: Abcam Plc, Cambridge, United Kingdom

    X
  • Daniel Sojka,

    Affiliation: Institute of Parasitology, Biology Centre, Academy of Sciences of the Czech Republic, České Budějovice, Czech Republic

    X
  • Debbie S. Ruelas,

    Affiliation: Sandler Center for Drug Discovery, California Institute for Quantitative Biosciences (QB3), University of California San Francisco, San Francisco, California, United States of America

    Current address: Gladstone Institute of Virology and Immunology, San Francisco, California, United States of America

    X
  • Brian Suzuki,

    Affiliation: Sandler Center for Drug Discovery, California Institute for Quantitative Biosciences (QB3), University of California San Francisco, San Francisco, California, United States of America

    X
  • Kee-Chong Lim,

    Affiliation: Sandler Center for Drug Discovery, California Institute for Quantitative Biosciences (QB3), University of California San Francisco, San Francisco, California, United States of America

    X
  • Stephanie D. Hopkins,

    Affiliation: Sandler Center for Drug Discovery, California Institute for Quantitative Biosciences (QB3), University of California San Francisco, San Francisco, California, United States of America

    X
  • James H. McKerrow,

    Affiliation: Sandler Center for Drug Discovery, California Institute for Quantitative Biosciences (QB3), University of California San Francisco, San Francisco, California, United States of America

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  • Conor R. Caffrey mail

    conor.caffrey@ucsf.edu

    Affiliation: Sandler Center for Drug Discovery, California Institute for Quantitative Biosciences (QB3), University of California San Francisco, San Francisco, California, United States of America

    X
  • Published: October 19, 2010
  • DOI: 10.1371/journal.pntd.0000850

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