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Research Article

A Pilot Study on Developing Mucosal Vaccine against Alveolar Echinococcosis (AE) Using Recombinant Tetraspanin 3: Vaccine Efficacy and Immunology

  • Zhisheng Dang,

    Affiliations: Division of Collaboration and Education, Research Center for Zoonosis Control, Hokkaido University, Sapporo, Hokkaido, Japan, State Key Laboratory of Veterinary Etiological Biology, Key Laboratory of Grazing Animal Diseases MOA, Key Laboratory of Veterinary Parasitology of Gansu Province, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Gansu, People's Republic of China

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  • Kinpei Yagi,

    Affiliation: Department of Biological Science, Hokkaido Institute of Public Health, Sapporo, Hokkaido, Japan

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  • Yuzaburo Oku,

    Affiliation: Parasitology Laboratory, School of Veterinary Medicine, Faculty of Agriculture, Tottori University, Tottori, Japan

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  • Hirokazu Kouguchi,

    Affiliation: Department of Biological Science, Hokkaido Institute of Public Health, Sapporo, Hokkaido, Japan

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  • Kiichi Kajino,

    Affiliation: Division of Collaboration and Education, Research Center for Zoonosis Control, Hokkaido University, Sapporo, Hokkaido, Japan

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  • Jun Matsumoto,

    Affiliation: Laboratory of Medical Zoology, Nihon University College of Bioresource Sciences, Fujisawa, Japan

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  • Ryo Nakao,

    Affiliation: Division of Collaboration and Education, Research Center for Zoonosis Control, Hokkaido University, Sapporo, Hokkaido, Japan

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  • Hiroyuki Wakaguri,

    Affiliation: Department of Medical Genome Science, Graduate School of Frontier Science, The University of Tokyo, Tokyo, Japan

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  • Atsushi Toyoda,

    Affiliations: RIKEN Genomic Sciences Center, Yokohama, Kanagawa, Japan, Comparative Genomics Laboratory, National Institute of Genetics, Mishima, Shizuoka, Japan

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  • Hong Yin,

    Affiliation: State Key Laboratory of Veterinary Etiological Biology, Key Laboratory of Grazing Animal Diseases MOA, Key Laboratory of Veterinary Parasitology of Gansu Province, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Gansu, People's Republic of China

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  • Chihiro Sugimoto mail

    sugimoto@czc.hokudai.ac.jp

    Affiliation: Division of Collaboration and Education, Research Center for Zoonosis Control, Hokkaido University, Sapporo, Hokkaido, Japan

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  • Published: March 27, 2012
  • DOI: 10.1371/journal.pntd.0001570

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