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Research Article

Diverse Inhibitor Chemotypes Targeting Trypanosoma cruzi CYP51

  • Shamila S. Gunatilleke equal contributor,

    equal contributor Contributed equally to this work with: Shamila S. Gunatilleke, Claudia M. Calvet

    Affiliations: Sandler Center for Drug Discovery, University of California San Francisco, San Francisco, California, United States of America, Department of Pathology, University of California San Francisco, San Francisco, California, United States of America

    X
  • Claudia M. Calvet equal contributor,

    equal contributor Contributed equally to this work with: Shamila S. Gunatilleke, Claudia M. Calvet

    Affiliations: Sandler Center for Drug Discovery, University of California San Francisco, San Francisco, California, United States of America, Cellular Ultra-Structure Laboratory, Oswaldo Cruz Institute (IOC), FIOCRUZ, Rio de Janeiro, Rio de Janeiro, Brazil

    X
  • Jonathan B. Johnston,

    Affiliation: Department of Pharmaceutical Chemistry, University of California San Francisco, San Francisco, California, United States of America

    X
  • Chiung-Kuang Chen,

    Affiliations: Sandler Center for Drug Discovery, University of California San Francisco, San Francisco, California, United States of America, Department of Pharmaceutical Chemistry, University of California San Francisco, San Francisco, California, United States of America

    X
  • Grigori Erenburg,

    Affiliation: King's University College at the University of Western Ontario, London, Ontario, Canada

    X
  • Jiri Gut,

    Affiliations: Sandler Center for Drug Discovery, University of California San Francisco, San Francisco, California, United States of America, Department of Pathology, University of California San Francisco, San Francisco, California, United States of America, Department of Medicine, University of California San Francisco, San Francisco, California, United States of America

    X
  • Juan C. Engel,

    Affiliations: Sandler Center for Drug Discovery, University of California San Francisco, San Francisco, California, United States of America, Department of Pathology, University of California San Francisco, San Francisco, California, United States of America

    X
  • Kenny K. H. Ang,

    Affiliation: Small Molecule Discovery Center, University of California San Francisco, San Francisco, California, United States of America

    X
  • Joseph Mulvaney,

    Affiliation: Small Molecule Discovery Center, University of California San Francisco, San Francisco, California, United States of America

    X
  • Steven Chen,

    Affiliation: Small Molecule Discovery Center, University of California San Francisco, San Francisco, California, United States of America

    X
  • Michelle R. Arkin,

    Affiliation: Small Molecule Discovery Center, University of California San Francisco, San Francisco, California, United States of America

    X
  • James H. McKerrow,

    Affiliations: Sandler Center for Drug Discovery, University of California San Francisco, San Francisco, California, United States of America, Department of Pathology, University of California San Francisco, San Francisco, California, United States of America

    X
  • Larissa M. Podust mail

    larissa.podust@ucsf.edu

    Affiliations: Sandler Center for Drug Discovery, University of California San Francisco, San Francisco, California, United States of America, Department of Pathology, University of California San Francisco, San Francisco, California, United States of America

    X
  • Published: July 31, 2012
  • DOI: 10.1371/journal.pntd.0001736

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