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Research Article

Affinity Is an Important Determinant of the Anti-Trypanosome Activity of Nanobodies

  • Guy Caljon mail,

    gcaljon@itg.be

    Affiliations: Department of Biomedical Sciences, Unit of Veterinary Protozoology, Institute of Tropical Medicine Antwerp, Antwerp, Belgium, Research Unit of Cellular and Molecular Immunology, Vrije Universiteit Brussel, Brussels, Belgium, Laboratory of Myeloid Cell Immunology, VIB, Brussels, Belgium

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  • Benoît Stijlemans,

    Affiliations: Research Unit of Cellular and Molecular Immunology, Vrije Universiteit Brussel, Brussels, Belgium, Laboratory of Myeloid Cell Immunology, VIB, Brussels, Belgium

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  • Dirk Saerens,

    Affiliations: Research Unit of Cellular and Molecular Immunology, Vrije Universiteit Brussel, Brussels, Belgium, Department of Structural Biology, VIB, Brussels, Belgium

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  • Jan Van Den Abbeele,

    Affiliation: Department of Biomedical Sciences, Unit of Veterinary Protozoology, Institute of Tropical Medicine Antwerp, Antwerp, Belgium

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  • Serge Muyldermans,

    Affiliations: Research Unit of Cellular and Molecular Immunology, Vrije Universiteit Brussel, Brussels, Belgium, Department of Structural Biology, VIB, Brussels, Belgium

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  • Stefan Magez,

    Affiliations: Research Unit of Cellular and Molecular Immunology, Vrije Universiteit Brussel, Brussels, Belgium, Department of Structural Biology, VIB, Brussels, Belgium

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  • Patrick De Baetselier

    Affiliations: Research Unit of Cellular and Molecular Immunology, Vrije Universiteit Brussel, Brussels, Belgium, Laboratory of Myeloid Cell Immunology, VIB, Brussels, Belgium

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  • Published: November 15, 2012
  • DOI: 10.1371/journal.pntd.0001902

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