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Research Article

A Phase Two Randomised Controlled Double Blind Trial of High Dose Intravenous Methylprednisolone and Oral Prednisolone versus Intravenous Normal Saline and Oral Prednisolone in Individuals with Leprosy Type 1 Reactions and/or Nerve Function Impairment

  • Stephen L. Walker mail,

    steve.walker@lshtm.ac.uk

    Affiliation: Department of Clinical Research, Faculty of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, London, United Kingdom

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  • Peter G. Nicholls,

    Affiliation: School of Health Sciences, University of Southampton, Southampton, United Kingdom

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  • Sushmita Dhakal,

    Affiliation: Anandaban Hospital, Kathmandu, Nepal

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  • Rachel A. Hawksworth,

    Affiliation: Anandaban Hospital, Kathmandu, Nepal

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  • Murdo Macdonald,

    Affiliation: Anandaban Hospital, Kathmandu, Nepal

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  • Kishori Mahat,

    Affiliation: Anandaban Hospital, Kathmandu, Nepal

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  • Shudan Ruchal,

    Affiliation: Anandaban Hospital, Kathmandu, Nepal

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  • Sushma Hamal,

    Affiliation: Anandaban Hospital, Kathmandu, Nepal

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  • Deanna A. Hagge,

    Affiliation: Anandaban Hospital, Kathmandu, Nepal

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  • Kapil D. Neupane,

    Affiliation: Anandaban Hospital, Kathmandu, Nepal

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  • Diana N. J. Lockwood

    Affiliation: Department of Clinical Research, Faculty of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, London, United Kingdom

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  • Published: April 12, 2011
  • DOI: 10.1371/journal.pntd.0001041

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