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Research Article

Inconsistent Protective Efficacy and Marked Polymorphism Limits the Value of Schistosoma japonicum Tetraspanin-2 as a Vaccine Target

  • Wenbao Zhang,

    Affiliation: Molecular Parasitology Laboratory, Australian Centre for International and Tropical Health and Nutrition, Queensland Institute of Medical Research, Brisbane, Queensland, Australia

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  • Jun Li,

    Affiliation: Molecular Parasitology Laboratory, Australian Centre for International and Tropical Health and Nutrition, Queensland Institute of Medical Research, Brisbane, Queensland, Australia

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  • Mary Duke,

    Affiliation: Molecular Parasitology Laboratory, Australian Centre for International and Tropical Health and Nutrition, Queensland Institute of Medical Research, Brisbane, Queensland, Australia

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  • Malcolm K. Jones,

    Affiliations: Parasite Cell Biology Laboratory, Queensland Institute of Medical Research, Brisbane, Queensland, Australia, The School of Veterinary Science, The University of Queensland, St Lucia, Queensland, Australia

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  • Ling Kuang,

    Affiliation: Molecular Parasitology Laboratory, Australian Centre for International and Tropical Health and Nutrition, Queensland Institute of Medical Research, Brisbane, Queensland, Australia

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  • Jianfeng Zhang,

    Affiliation: Molecular Parasitology Laboratory, Australian Centre for International and Tropical Health and Nutrition, Queensland Institute of Medical Research, Brisbane, Queensland, Australia

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  • David Blair,

    Affiliation: School of Marine and Tropical Biology, James Cook University, Townsville, Queensland, Australia

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  • Yuesheng Li,

    Affiliations: Molecular Parasitology Laboratory, Australian Centre for International and Tropical Health and Nutrition, Queensland Institute of Medical Research, Brisbane, Queensland, Australia, Hunan Institute of Parasitic Diseases, Yueyang, China

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  • Donald P. McManus mail

    donM@qimr.edu.au

    Affiliation: Molecular Parasitology Laboratory, Australian Centre for International and Tropical Health and Nutrition, Queensland Institute of Medical Research, Brisbane, Queensland, Australia

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  • Published: May 31, 2011
  • DOI: 10.1371/journal.pntd.0001166

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