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Research Article

Local Increase of Arginase Activity in Lesions of Patients with Cutaneous Leishmaniasis in Ethiopia

  • Tamrat Abebe,

    Affiliations: Department of Microbiology, Immunology and Parasitology, Addis Ababa University, Addis Ababa, Ethiopia, Department of Biochemistry, WHO Immunology Research and Training Center, University of Lausanne, Lausanne, Switzerland

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  • Asrat Hailu,

    Affiliation: Department of Microbiology, Immunology and Parasitology, Addis Ababa University, Addis Ababa, Ethiopia

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  • Mihretu Woldeyes,

    Affiliation: Department of Dermatology and Venerology, Addis Ababa University, Addis Ababa, Ethiopia

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  • Woinshet Mekonen,

    Affiliation: Department of Microbiology, Immunology and Parasitology, Addis Ababa University, Addis Ababa, Ethiopia

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  • Kassahun Bilcha,

    Affiliation: Department of Dermatovenerology, Gondar University, Gondar, Ethiopia

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  • Thomas Cloke,

    Affiliation: Section of Immunology, Department of Medicine, Imperial College London, London, United Kingdom

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  • Lionel Fry,

    Affiliation: Department of Medicine, Imperial College London, London, United Kingdom

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  • Nafisa-Katrin Seich al Basatena,

    Affiliation: Section of Immunology, Department of Medicine, Imperial College London, London, United Kingdom

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  • Karina Corware,

    Affiliation: Section of Immunology, Department of Medicine, Imperial College London, London, United Kingdom

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  • Manuel Modolell,

    Affiliation: Department of Cellular Immunology, Max-Planck-Institute for Immunobiology and Epigenetics, Freiburg, Germany

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  • Markus Munder,

    Affiliation: Third Department of Medicine (Hematology, Oncology, and Pneumology), University Medical Center Mainz, Mainz, Germany

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  • Fabienne Tacchini-Cottier,

    Affiliation: Department of Biochemistry, WHO Immunology Research and Training Center, University of Lausanne, Lausanne, Switzerland

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  • Ingrid Müller equal contributor mail,

    equal contributor Contributed equally to this work with: Ingrid Müller, Pascale Kropf

    i.muller@imperial.ac.uk (IM); Pascale.Kropf@lshtm.ac.uk (PK)

    Affiliation: Section of Immunology, Department of Medicine, Imperial College London, London, United Kingdom

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  • Pascale Kropf equal contributor mail

    equal contributor Contributed equally to this work with: Ingrid Müller, Pascale Kropf

    i.muller@imperial.ac.uk (IM); Pascale.Kropf@lshtm.ac.uk (PK)

    Affiliation: Infection and Immunology Department, London School of Hygiene and Tropical Medicine, London, United Kingdom

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  • Published: June 12, 2012
  • DOI: 10.1371/journal.pntd.0001684

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