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Research Article

Targeting the Non-structural Protein 1 from Dengue Virus to a Dendritic Cell Population Confers Protective Immunity to Lethal Virus Challenge

  • Hugo R. Henriques equal contributor,

    equal contributor Contributed equally to this work with: Hugo R. Henriques, Eline V. Rampazo

    Affiliation: Laboratory of Antigen Targeting to Dendritic Cells, Department of Parasitology, University of São Paulo, São Paulo, Brazil

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  • Eline V. Rampazo equal contributor,

    equal contributor Contributed equally to this work with: Hugo R. Henriques, Eline V. Rampazo

    Affiliation: Laboratory of Antigen Targeting to Dendritic Cells, Department of Parasitology, University of São Paulo, São Paulo, Brazil

    X
  • Antonio J. S. Gonçalves,

    Affiliation: Laboratory of Biotechnology and Physiology of Viral Infections, Oswaldo Cruz Institute, Oswaldo Cruz Foundation, Rio de Janeiro, Brazil

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  • Elaine C. M. Vicentin,

    Affiliation: Laboratory of Antigen Targeting to Dendritic Cells, Department of Parasitology, University of São Paulo, São Paulo, Brazil

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  • Jaime H. Amorim,

    Affiliation: Laboratory of Vaccine Development, Department of Microbiology, University of São Paulo, São Paulo, Brazil

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  • Raquel H. Panatieri,

    Affiliation: Laboratory of Antigen Targeting to Dendritic Cells, Department of Parasitology, University of São Paulo, São Paulo, Brazil

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  • Kelly N. S. Amorim,

    Affiliation: Laboratory of Antigen Targeting to Dendritic Cells, Department of Parasitology, University of São Paulo, São Paulo, Brazil

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  • Marcio M. Yamamoto,

    Affiliation: Laboratory of Antigen Targeting to Dendritic Cells, Department of Parasitology, University of São Paulo, São Paulo, Brazil

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  • Luís C. S. Ferreira,

    Affiliations: Laboratory of Vaccine Development, Department of Microbiology, University of São Paulo, São Paulo, Brazil, National Institute for Science and Technology in Vaccines, Belo Horizonte, Brazil

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  • Ada M. B. Alves,

    Affiliations: Laboratory of Biotechnology and Physiology of Viral Infections, Oswaldo Cruz Institute, Oswaldo Cruz Foundation, Rio de Janeiro, Brazil, National Institute for Science and Technology in Vaccines, Belo Horizonte, Brazil

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  • Silvia B. Boscardin mail

    sbboscardin@usp.br

    Affiliations: Laboratory of Antigen Targeting to Dendritic Cells, Department of Parasitology, University of São Paulo, São Paulo, Brazil, National Institute for Science and Technology in Vaccines, Belo Horizonte, Brazil

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  • Published: July 18, 2013
  • DOI: 10.1371/journal.pntd.0002330

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