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Featured Editorial

The Global Atlas of Helminth Infection: Mapping the Way Forward in Neglected Tropical Disease Control

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Improvements in the diagnosis and monitoring of NTDs need to be accompanied by better intelligence about where the diseases occur. New mapping techniques enable the Global Atlas of Helminth Infection, an open-access catalog of the distribution and prevalence of schistosomiasis and soil-transmitted helminth infection. Such resources can aid decision-making in NTD control.

 

Featured Viewpoints

Clinical Research in Resource-Limited Settings: Enhancing Research Capacity and Working Together to Make Trials Less Complicated

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Trudie Lang and colleagues suggest that true capacity-building might be best achieved by establishing a community of developing country–based researchers to share locally derived solutions and build a set of validated methods and operational tools that will enable locally led development.

 

Featured Research

The Jacob2 Lectin of the Entamoeba histolytica Cyst Wall Binds Chitin and Is Polymorphic

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With this study, Ghosh et al. have made steps toward deciphering Eh cyst wall structure vis-a-vis the surface lectins- Jacob and Jessie. Their findings highlight the relative immunogenicity of the different Jacob/Jessie lectins in human sera.

 

Comparing Diagnostic Accuracy of Kato-Katz, Koga Agar Plate, Ether-Concentration, and FLOTAC for Schistosoma mansoni and Soil-Transmitted Helminths

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Accurate diagnosis of infections with parasitic worms is important for optimal patient management and for monitoring deworming programs. Through their efforts to test diagnostic methods currently in use, Glinz and colleagues have identified that which is most sensitive for S. mansoni.

 

A Tractable Experimental Model for Study of Human and Animal Scabies

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The pig/mite model reported here will facilitate in vivo studies on host immune responses to scabies, including relations to associated bacterial pathogenesis, and more detailed studies of molecular evolution and host adaptation.

 

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