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05/09/2024

Viewpoints

FDA’s proposed rule and its regulatory impact on emerging and reemerging neglected tropical diseases in the United States

Diagnosing infectious diseases significantly influences patient care, aiding in outbreak identification, response, and public health monitoring. However, the range of FDA-approved molecular tests remains notably limited, especially concerning neglected tropical diseases (NTDs). Drawing upon our experience as one of the largest healthcare networks in the greater...

Image credit: jarmoluk, Pixabay

FDA’s proposed rule and its regulatory impact on emerging and reemerging neglected tropical diseases in the United States

05/08/2024

Research Article

Variability in antivenom neutralization of Mexican viperid snake venoms

Each year, 3,800 cases of snakebite envenomation are reported in Mexico, resulting in 35 fatalities. The only scientifically validated treatment for snakebites in Mexico is the use of antivenoms. Currently, two antivenoms are available in the market, with one in the developmental phase. These antivenoms, produced in horses, consist of F(ab’)2 fragments generated using venoms from various species as immunogens. While previous studies primarily focused on...

Image credit: Cataloging Nature, Flickr

Variability in antivenom neutralization of Mexican viperid snake venoms

05/01/2024

Viewpoints

Elimination of human African trypanosomiasis: The long last mile

They said the last mile would be the hardest. The challenge to eliminate human African trypanosomiasis caused by Trypanosoma brucei gambiense (gHAT) could have entered that most difficult stretch. The fifth stakeholders’ meeting on gambiense and rhodesiense HAT, convened by the World Health Organisation (WHO) in Geneva (7–9 June 2023)...

Elimination of human African trypanosomiasis: The long last mile

Image credit: CDC

04/25/2024

Research Article

Climate-driven models of leptospirosis dynamics in tropical islands from three oceanic basins

Leptospirosis is a neglected zoonosis which remains poorly known despite its epidemic potential, especially in tropical islands where outdoor lifestyle, vulnerability to invasive reservoir species and hot and rainy climate constitute higher risks for infections. Burden remains poorly documented while outbreaks can easily overflow health systems of these...

Climate-driven models of leptospirosis dynamics in tropical islands from three oceanic basins

Image credit: pntd.0011717

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PLOS Neglected Tropical Diseases | ISSN: 1935-2735 (online)